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KMID : 1189120170140020049
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대한의학유전학회지
2017 Volume.14 No. 2 p.49 ~ p.55
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Biomarkers and genetic factors for early prediction of pre-eclampsia
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Kim Han-Nah
Shim Sung-Shin
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Abstract
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Pre-eclampsia is known to cause considerable maternal morbidity and mortality. Thus, many studies have examined the etiopathogenesis of pre-eclampsia. While many pathophysiological factors related to pre-eclampsia have been identified, the precise etiopathogenesis of pre-eclampsia remains unclear. Numerous studies have identified factors for the early prediction for pre-eclampsia to lead to preparation and closer observation on pre-eclampsia when it occurs. This article reviews on current studies of biomarkers and genetic factors related to pre-eclampsia, which may be important for developing strategies for early prediction of pre-eclampsia.
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KEYWORD
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Pre-eclampsia, Biomarkers, Genes, Cell-free nucleic acids, Early detection of disease
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